Entering the safe mode allows Outlook to open with only essential configurations and without loading the add-ins. After closing the Outlook app, it will revert back to the normal mode the next time you open it. So, whenever you need to open in the safe mode, you can follow the methods mentioned below in the article.

Using the Run Command

You can enter a command in the Run window to open Outlook in safe mode.  Alternatively, you can use the command prompt as follows.

Using the Ctrl Key on Keyboard

To open Outlook in safe mode using the Ctrl key, 

Use the Shortcut 

You can create a shortcut and run it each time you need to open Outlook in safe mode. To quickly open the shortcut, we will be creating the shortcut on the desktop. If you don’t find it, open your C: drive and search for Outlook.exe in the search bar at the top right corner. Then, right-click on Outlook.exe and select Copy as path option.

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